Steam-sterilizable separator systems were developed for the treatment of fermentation broths under sterile conditions. The system with the separator CSC 4 comes as a complete package unit with automatic or manual in-place steam sterilization. Steam sterilization takes place at 1.5 bar steam pressure and 127 °C. The hydrohermetic feed system assures closed product feed and guarantees gentle treatment of shear-sensitive micro-organisms. A hydrostop-system ensures controlled partial ejection for precise solids discharge. Typical fields of application are the production of starter cultures for the food and pharmaceutical sector, the recovery of biomass for pharmaceutical products or the gentle discharge of biomass with product-damaging cell constituents. The closed machine and plant concept (biocontainment) also enables the processing of genetically engineered micro-organisms and vaccines. Running noise is reduced by double-walled hoods and solids collectors and connection to a closed cooling system up to 1 bar overpressure.
Further information cpp 218